Table 5.

Predictive value of GRSs in Afro-Caribbeans after adjustment with TCRFs

Multivariate logistic regression for CHD (N = 537)
	OR	95% CI	P value
NW_GRS19	1.40	(1.09-1.80)	8 × 10−3
W_GRS19	1.20	(0.94-1.53)	0.14
NW_GRS14	1.43	(1.12-1.83)	4 × 10−3
W_GRS14	1.25	(0.99-1.59)	0.06

ORs are expressed per 1 standard deviation change and were calculated from model incorporating each GRS, age, sex, hypertension, diabetes, hypercholesterolemia, and smoking.

CI, confidence interval; GRS, genetic risk score; NW, nonweighted; OR, odds ratio; TCRFs, traditional cardiovascular risk factors; W, weighted.