Table 1.

Measured oxidatively damaged DNA bases in Ku70^–/– genomic DNA 4 hr post-damage induction^a (adapted from Gassman et al. 2015).

Exposure	DNA lesion/106 DNA bases (mean ± SD, n > 3)b
	ThyGly	FapyAde	FapyGua	8-oxoGua
Control	3.82 ± 1.32	2.83 ± 0.98	3.69 ± 1.41	0.98 ± 0.16
BPA	8.41 ± 0.45*	3.72 ± 1.37	5.19 ± 0.92	1.21 ± 0.40
KBrO3	5.11 ± 0.69	4.01 ± 0.86	4.60 ± 0.92	1.33 ± 0.55
BPA + KBrO3	7.48 ± 0.48*†	4.38 ± 0.41*	6.77 ± 1.36*†	1.55 ± 0.59
aSamples treated with 150 μM BPA only were exposed for 5 hr; those treated with 20 mM KBrO3 only were exposed for 1 hr, then medium was replaced for 3 hr; and samples co-exposed to 150 μM BPA were exposed for 1 hr, then exposed to 150 μM BPA + 20 mM of KBrO3 for 1 hr, followed by exposure for 3 hr to 150 μM BPA only. bMeasurements were made by GC/MS as described in “Methods.” *p < 0.05 compared with untreated controls. †p < 0.05 compared with KBrO3.