Table 5.

Selected DNA repair genes identified 4 hr post-damage induction^a, with the magnitude of the fold change over control for genes with p values < 0.05.

BPA	Fold changeb	KBrO3	Fold change	BPA + KBrO3	Fold change
Apex1	n.c.	Apex1	n.c.	Apex1	1.58
Ercc3	n.c.	Ercc3	n.c.	Ercc3	1.45
Ercc5	n.c.	Ercc5	–1.49	Ercc5	n.c.
Ercc6	n.c.	Ercc6	n.c.	Ercc6	2.62
Ercc8	n.c.	Ercc8	4.63	Ercc8	6.36
Exo1	1.60	Exo1	2.33	Exo1	3.40
Fen1	n.c.	Fen1	1.73	Fen1	1.90
Lig3	n.c.	Lig3	n.c.	Lig3	2.02
Lig4	n.c.	Lig4	n.c.	Lig4	2.4
Mre11	n.c.	Mre11	n.c.	Mre11	2.27
Mutyh	n.c.	Mutyh	–3.33	Mutyh	–2.20
Ogg1	n.c.	Ogg1	–1.68	Ogg1	–2.00
Parp1	n.c.	Parp1	–1.28	Parp1	–1.39
Rad51	1.83	Rad51	–3.11	Rad51	–2.49
Rpa1	n.c.	Rpa1	1.56	Rpa1	1.53
Tdg1	n.c.	Tdg1	2.12	Tdg1	2.82
Tdp1	n.c.	Tdp1	1.44	Tdp1	1.66
Genes unique to 4 hr
Mpg	n.c.	Mpg	–1.91	Mpg	–2.59
Neil1	n.c.	Neil1	–2.48	Neil1	–2.46
Neil3	n.c.	Neil3	–6.24	Neil3	–11.36
PolB	n.c.	PolB	n.c.	PolB	–2.90
PolL	n.c.	PolL	–3.49	PolL	–2.92
Xrcc1	n.c.	Xrcc1	–1.72	Xrcc1	–1.76
n.c., No significant change over control. aSamples treated with 150 μM BPA only were exposed for 5 hr; those treated with 20 mM KBrO3 only were exposed for 1 hr, then medium was replaced for 3 hr; and samples co-exposed to 150 μM BPA were exposed for 1 hr, then exposed to 150 μM BPA + 20 mM of KBrO3 for 1 hr, followed by exposure for 3 hr to 150 μM BPA only. bGene expression fold change was evaluated in comparison with untreated control with all p-values < 0.05.