Table 7.
Intracellular pHa in controls and in treated cells (mean ± SD).
Exposure | 4 hb | 24 hb |
---|---|---|
Control | 7.5 ± 0.11 | 7.5 ± 0.08 |
BPA | 7.5 ± 0.28 | 7.5 ± 0.11 |
KBrO3 | 6.8 ± 0.11* | 7.8 ± 0.26 |
BPA + KBrO3 | 7.2 ± 0.08† | 7.0 ± 0.14*† |
aIntracellular pH was quantified by flow cytometry using pHRodo®. bSamples treated with 150 μM BPA only were exposed for 5 or 25 hr; those treated with 20 mM KBrO3 only were exposed for 1 hr, then medium was replaced for 3 or 23 hr; and co-exposed samples were exposed to 150 μM BPA for 1 hr, then to 150 μM BPA + 20 mM KBrO3 for 1 hr, followed by exposure to 150 μM BPA only for 3 or 23 hr. *p < 0.05 compared with untreated controls. †p < 0.05 compared with KBrO3 alone. |