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. 2016 Aug 2;11:3655–3675. doi: 10.2147/IJN.S111279

Figure 5.

Figure 5

Effect of Sal, AgNPs, or both Sal and AgNPs on cytotoxicity in human ovarian cancer cells.

Notes: (A) The cells were treated with Sal (3 µM), AgNPs (4 µg/mL), or the combination of Sal (3 µM) and AgNPs (4 µg/mL) for 24 hours. LDH activity was measured at 490 nm using the LDH Cytotoxicity Kit. (B) ROS were measured with relative fluorescence of 2′,7′-dichlorofluorescein using a spectrofluorometer. The results are expressed as mean ± standard deviation of three independent experiments. The treated groups showed statistically significant differences from the control group by the Student’s t-test (*P<0.05).

Abbreviations: AgNPs, silver nanoparticles; Con, control; LDH, lactate dehydrogenase; ROS, reactive oxygen species; Sal, salinomycin.