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. 2016 Aug 4;10:2499–2506. doi: 10.2147/DDDT.S110742

Table 1.

Release kinetics of RPC-loaded microspheres

Model Free RPC
RPC-loaded microspheres
Equation Correlation coefficient (r2) Equation Correlation coefficient (r2)
First order ln(1− Q) =3.276t −1.092 0.9432 ln(1− Q) =5.276t +0.562 0.9534
Higuchi Q =8.211t½+1.219 0.9821 Q =8.627t½+1.921 0.9812
Korsmeyer–Peppas lnQ =0.256lnt −0.627 0.9525 lnQ =1.287lnt +0.192 0.9546
Weibull lnln(1/(1− Q)) =3.291lnt −1.281 0.9829 lnln(1/(1− Q)) =1.982lnt +0.261 0.9931

Abbreviation: RPC, ropivacaine.