Table 2.

Characterization of the zeta-potential of the NLC, M-NLC, NLC-RFB, and M-NLC-RFB formulations

Formulation	Zeta-potential (mV)
NLC	−20.5±0.8
M-NLC	+48.7±2.1a
NLC-RFB	−17.9±1.9
M-NLC-RFB	+37.6±1.0a–c

Notes: All values represent the mean ± standard deviation (n=3).

^aStatistically different (P<0.05) between NLCs and conjugated formulations.

^bStatistically different (P<0.05) between unloaded conjugated NLCs and RFB loaded conjugated NLCs.

^cStatistically different (P<0.05) between loaded NLCs nonconjugated and loaded NLCs conjugated.

Abbreviations: NLC, nanostructured lipid carrier; M, mannose; RFB, rifabutin.