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Value of R2 obtained from the release of RFB from the NLC-RFB lyophilized formulation for different models of mechanism of drug release
| pH | Zero order | First order | Hixson–Crowell | Higuchi | Korsmeyer–Peppas |
|---|---|---|---|---|---|
| 5.0 | 0.919 | 0.655 | 0.660 | 0.993 | 0.743 |
| 6.2 | 0.968 | 0.839 | 0.899 | 0.981 | 0.969 |
| 7.4 | 0.821 | 0.506 | 0.660 | 0.944 | 0.801 |
Abbreviations: RFB, rifabutin; NLC, nanostructured lipid carrier.
