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. 2016 Aug 4;11:3621–3640. doi: 10.2147/IJN.S104623

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© 2016 Madureira et al. This work is published and licensed by Dove Medical Press Limited

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Necrotic (Annexin V+/7AAD+) and apoptotic (Annexin V+/7AAD−) lymphocytes % (mean ± SD) after treatment with free RA, sage extract, and WSLN and CSLN (CSLN) at two concentrations.

Notes: Empty SLN used only one lipid concentration (0.5% [m/v]) for the two polyphenol and extract concentrations. ^*Mean value is different from positive control (C+) and is statistically significant (P<0.05).

Abbreviations: RA, rosmarinic acid; CSLN, Carnauba solid lipid nanoparticles; WSLN, Witepsol solid lipid nanoparticles; SD, standard deviation; C+, positive control; C−, negative control.