Fig. 1.
Hyaluronic acid sponge with zinc system. A, Hyaluronan sponge system with soluble hyaluronan of large molecular weight, soluble hyaluronan of small molecular weight, and biologically active molecules still within the sponge system. Stratum corneum is not hydrated and thinner. B, Hyaluronan sponge system with soluble hyaluronan of large molecular weight, soluble hyaluronan of small molecular weight, and biologically active molecules transferred into the layers of skin. Surface of skin and skin layers are kept hydrated by this mechanism. Stratum corneum is well hydrated and thicker. Reprinted with permission from Hylaco LLC.