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. 2016 Jul 11;4(7):e792. doi: 10.1097/GOX.0000000000000734

Fig. 1.

Fig. 1.

Hyaluronan sponge system. A, Hyaluronan sponge system with soluble hyaluronan large molecular weight, soluble hyaluronan small molecular weight, and biologically active molecule still within the sponge system. Stratum corneum is not hydrated and thinner. B, Hyaluronan sponge system with soluble hyaluronan large molecular weight, soluble hyaluronan small molecular weight, and biologically active molecule transferred into the layers of skin. Surface of skin and skin layers are kept hydrated by this mechanism. Stratum corneum is well hydrated and thicker. Reprinted with permission from Hylaco LLC.