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. 2016 Aug 9;10:191. doi: 10.3389/fncel.2016.00191

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Copyright © 2016 Herzine, Laugeray, Feat, Menuet, Quesniaux, Richard, Pichon, Montécot-Dubourg, Perche and Mortaud.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Signaling pathways involving the cytoskeleton remodeling. Here we show proteins whose expression is deregulated in GLA0.2- (A) and GLA1-exposed pups (B). Significant number of deregulated genes after perinatal exposure to GLA, involved in cell migration and cytoskeleton dynamics can cause problems at cellular levels of migration and adhesion and even vesicular transport in the cell. Figure from David Software database and adapted by S. Mortaud. Differentially regulated cytoskeleton genes were determined using a one-way ANOVA analysis and a Benjamini Hochberg False Discovery Rate (FDR) (< 0.05) method for multiple comparison corrections.