Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Aug 9;6:31226. doi: 10.1038/srep31226

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a,b) Typical current traces evoked by a holding potential (Vh) of −60 mV stimulating astrocytes with a voltage ramp or voltage step family (insets). Astrocytes (left panels) plated on PDL displayed only voltage-dependent outward rectifying K⁺ conductance. Astrocytes plated on HTlc coated coverslips (Right panels), display an inward conductance in response to a hyperpolarizing stimulus that is inhibited after extracellular superfusion with Ba²⁺ (a, inset, red trace 2). Note inhibition by Ba²⁺ of outward currents in HTLc-treated astrocytes, suggesting a weak rectification profile of the inward current typical of Kir4.1. (c) Micrograph of calcein-loaded astrocytes showing the different shape of astrocytes grown on PDL vs those grown on HTlc. Histogram summarizing the swelling rates (τ) for the astrocytes grown on PDL or on HTlc. Value is the mean ± SE. (n = 30; P < 0.05).