Figure 3. Expression of the nuclear cellular proliferation antigen in infarcted animals submitted or not to treatment with VEGF165. The values indicate the mean and standard deviation by analysis of the expression index, after digital quantification of the immunohistochemical reactions, as is described in methods. The number of animals in each group was 10 (n=10). Asterisks (*) indicated the p values obtained for each marker, comparing the results acquired of animals treated with VEGF versus the non-treated group. *p=0.0078; **p=0.0006. SAMI: group of animals submitted to acute myocardial infarction (small infarction) without treatment; SAMI + VEGF: group of animals submitted to acute myocardial infarction (small infarction) treated with gene transfer containing VEGF165; LAMI: group of animals submitted to acute myocardial infarction (large infarction) without treatment; LAMI + VEGF: group of animals submitted to acute myocardial infarction (large infarction) treated with gene transfer containing VEGF165.