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. 2016 Aug 8;16:611. doi: 10.1186/s12885-016-2659-5

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Pathway enrichment analysis. In total, 64 biological processes (rows) were significantly (FDR < 0.05) enriched for at least one volumetric feature (columns) as indicated by an asterisk. Heatmap shows normalized enrichment scores (NES) calculated with Gene Set Enrichment Analysis. Positive NES (blue) correspond to correlated pathways and negative NES (yellow) correspond to anti-correlated pathways