Table 1.
Significant protein expressions of uPAS components and tumour-associated markers
| Tumour marker 1 | Tumour marker 2 | p-values |
|---|---|---|
| uPAR | IGF1R | 0.0011 |
| Cathepsin B | 0.0034 | |
| Cathepsin D | 0.0075 | |
| c-Met | 0.0229 | |
| IR | 0.0215 | |
| Plasminogen | 0.0105 | |
| uPA | PAI-1 | ≤0.00001 |
| Cathepsin D | 0.0187 | |
| Plasminogen | 0.0237 | |
| Ki67 | 0.0004 (inverse) | |
| IGF1R | IR | 0.0020 |
| Cathepsin B | 0.0002 | |
| uPARAP | 0.0168 | |
| Plasminogen | 0.0237 | |
| Ki67 | 0.0120 | |
| PTEN | ≤0.00001 | |
| PAI-1 | Ki67 | 0.00006 (inverse) |
| c-Met | IR | 0.0364 |
| Plasminogen | 0.0096 | |
| uPARAP | 0.0097 | |
| Ki67 | 0.0486 | |
| IR | Plasminogen | 0.0075 |
| PTEN | 0.0083 | |
| Ki67 | 0.0309 |
Protein expressions were determined using IHC technique followed by statistical analyses. Correlations of parameters marked in bold are described within the text in more detail