Table 1.
Day | Control | MK-801 | ||
---|---|---|---|---|
| ||||
- | Olanzapine | Haloperidol | ||
1 | 49.8±4.9 | 60.0±0.0 | 60.0±0.0 | 57.1±2.9 |
2 | 36.1±7.3 | 56.3±2.5 | 57.8±2.2 | 47.4±6.7 |
3 | 34.0±5.5 | 56.1±3.9 | 52.4±3.4 | 51.0±8.6 |
4 | 37.0±6.3 | 59.4±0.6 | 46.4±1.2 | 54.5±3.4 |
5 | 29.2±5.6 | 51.8±3.2 | 45.6±3.0 | 37.0±7.6 |
6 | 18.3±3.0 | 56.7±2.3* | 46.7±4.4 | 41.1±8.3 |
7 | 18.9±5.2 | 50.1±5.9* | 32.3±5.8 | 40.3±10.1 |
8 | 28.8±6.3 | 57.9±2.0* | 24.7±5.6† | 45.3±4.3 |
9 | 20.0±3.7 | 46.6±6.4* | 30.8±7.0 | 40.2±4.3 |
Values are presented as mean±standard error of mean for six animals per group.
In each trial, mice were placed in the pool at a single starting position and allowed to swim freely until they found the platform. The time required to escape onto the hidden platform was recorded.
p<0.05 vs. control group,
p<0.05 vs. MK-801-treated group.