Table 1.
Baseline characteristics of study participants
| N (male/female) | 173 (68/105) |
| Age (years) | 63 (53-70) |
| Duration of hypertension (year) | 9 (3-16) |
| Diabetes [n (%)] | 38 (22) |
| CV disease [n (%)] | 26 (15) |
| Current smoker [n (%)] | 33 (19.1) |
| Body height [cm] | 168 (160-174) |
| Body weight [kg] | 80 (70-90) |
| BMI [kg/m2] | 27.8 (25.3-31.2) |
| Blood glucose [mmol/l] | 5.6 (5.1-6.6) |
| GFR-EPI [ml/min/1.73 m2] | 81.9 (67.9-90) |
| Uric acid [μmol/l] | 324.2 ± 79.6 |
| Total cholesterol [mmol/l] | 5.2 ± 1.1 |
| Triglyceride [mmol/l] | 1.4 (1.1-2.1) |
| Medications | |
| ACE-inhibitor [n (%)] | 116 (67.1) |
| ARB [n (%)] | 35 (20.2) |
| Calcium channel blocker [n (%)] | 88 (50.9) |
| Beta-blocker [n (%)] | 98 (56.6) |
| Diuretic [n (%)] | 72 (41.6) |
| Antiplatelet drug [n (%)] | 52 (30.1) |
| Statin [n (%)] | 57 (33.4) |
| Alprazolam [n (%)] | 23 (13.3) |
| TEMPS-A, BDI, HAM-A scores | |
| Depressive | 6 (4-9) |
| Cyclothymic | 3 (1-5) |
| Hyperthymic | 12 (9-14) |
| Irritable | 3 (2-6) |
| Anxious | 4 (2-9) |
| BDI | 5 (2-9) |
| HAM-A | 5 (2-10) |
| Hemodynamic. arterial stiffness parameters | |
| Heart rate [1/min] | 70.8 (64.8-78) |
| SBPbrach [mmHg] | 133.5 ± 12 |
| DBPbrach [mmHg] | 75.6 ± 9.2 |
| PPbrach [mmHg] | 54.2 (47.1-62.4) |
| SBPcentr [mmHg] | 123 (113.2-130.8) |
| PPcentr [mmHg] | 51 (43.5-60.4) |
| PPAmp | 1.07 (1.00-1.13) |
| PWV (m/sec) | 8.7 (7.7-9.9) |
| Aix (%) | 15.5 (8.5-25.2) |
Data are presented as mean ± SD or median (interquartile range). Categorical parameters are presented as n (%). CV diseases cardiovascular diseases, BMI body mass index, GFR-EPI glomerular filtration rate assessed by the chronic kidney disease epidemiology collaboration glomerular filtration rate equation, ACE Angiotensin converting enzyme, ARB angiotensin II receptor blocker, TEMPS-A Temperament Evaluation of Memphis Pisa, Paris and San Diego questionnaire, BDI Beck Depression Inventory, HAM-A Hamilton Anxiety Scale, SBPbrach brachial systolic pressure, DBPbrach brachial diastolic pressure, PPbrach brachial pulse pressure, SBPcentr central systolic pressure, PPcentr central pulse pressure, PPAmp pulse pressure amplification, PWV carotid-femoral pulse wave velocity, Aix augmentation index