TABLE 2.
Summary of Correlation, Regression, and Deviation Analyses
| Dataset combination | KRC | Pearson r (95% CI) | Passing–Bablok | Bland–Altman | |||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| P† | Mean % difference (95% CI) | 95% limits of agreement (lower; upper) | |||||||
|
| |||||||||
| P* | Slope (95% CI) | Intercept (95% CI) | Residual SD (95% CI) | ||||||
| FD-SD1 (clinical) n = 29 |
k3 | 0.95 (0.89–0.98) | 0.58 | 1.08 (0.94–1.32) | −6.0E-6 (−6.1E-4 to 5.3E-4) | 3.4E-4 (−6.7E-4 to 6.7E-4) | 0.20 | −10 (−16 to −4) | −40; 21 |
|
| |||||||||
| K1 | 1.00 (0.99–1.00) | 0.58 | 0.99 (0.97–1.00) | 0.0045 (−1.3E-4 to 0.011) | 0.0058 (−0.011 to 0.011) | 1.00 | −1 (−2 to 1) | −7; 5 | |
|
| |||||||||
| FD-SD2 (clinical) n = 26 |
k3 | 0.85 (0.69–0.93) | 1.00 | 1.40 (1.01–1.86) | −6.8 E-4 (−0.0020 to 4.7E-4) | 6.3E-4 (−0.0012 to 0.0012) | Analysis not conducted | Analysis not conducted | Analysis not conducted |
|
| |||||||||
| K1 | 1.00 (0.99–1.00) | 0.86 | 1.04 (0.99–1.08) | −0.012 (−0.024 to 2.2E-4) | 0.0060 (−0.012 to 0.012) | 1.00 | 0 (−2 to 1) | −8; 7 | |
|
| |||||||||
| FD-SD2 (preclinical) n = 21 |
k3 | 0.91 (0.79–0.96) | 0.98 | 1.10 (0.89–1.38) | 5.2E-4 (−5.1E-4 to 0.0013) | 8.2E-4 (−0.0016 to 0.0016) | 0.82 | −26 (−43 to −8) | −100; 49 |
|
| |||||||||
| K1 | 1.00 (0.99–1.00) | 0.98 | 1.02 (0.98–1.06) | −0.0013 (−0.0079 to 0.0069) | 0.0038 (−0.0075 to 0.0075) | 1.00 | −1 (−2 to 0) | −5; 3 | |
*
Cumulative sum test.
†
Kolmogorov–Smirnov test.
FD = full dataset (~170 min in clinical, 90 min in preclinical studies); SD1 = first shortened dataset (~100 min); SD2 = second shortened dataset (45 min).