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Lack of β1 adrenergic receptor on glucose, insulin tolerance of mice kept on a chow diet or on a HFD. (A and B) Blood glucose levels before and after i.p. administration of 2 g/kg glucose (GTT) or (C and D) after i.p. injection of 0·5 U/kg insulin (ITT) at the indicated time points in WT and β1KO animals kept on chow or high-fat diet; A) *P<0·05 vs WT, **P<0·05 vs β1KO,+P<0·001 vs WT, ×P<0·001 vs β1KO; C) *P<0·01 vs. WT; **P<0·01 vs β1KO; ×P<0·01 vs WT.
