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. 2016 Jul 21;1(11):e87168. doi: 10.1172/jci.insight.87168

Figure 3. CPI-203 potently suppresses Th17 downstream chemokines and cytokines in HBE cells.

Figure 3

HBE cell lines from 3 CF and 3 non-CF (labeled as HBE) donors were established in the air-liquid interphase culture and treated with vehicle (Veh) or 200 nM CPI-203 (CPI) for 3 days. (A) Culture supernatants were harvested for analysis on proinflammatory chemokines and cytokines by Luminex, and (B) RNA-seq was conducted on the cells and relative gene expression is shown. *P < 0.05, **P < 0.005, ***P < 0.0005 by ANOVA.