Table 3.
African–American | Whites | P value | |||||
---|---|---|---|---|---|---|---|
Diabetes | Prediabetes | Normal glucose | Diabetes | Prediabetes | Normal glucose | ||
Carotid-femoral PWV | |||||||
N | 344 | 443 | 144 | 746 | 1,897 | 705 | |
Differencea (cm/s) | 69.3 | 13.6 | 0 | 106 | 22.3 | 0 | |
95% CI | 4.1, 134.6 | −47.3, 74.4 | ref. | 77.2, 134.7 | −0.9, 45.6 | ref. | |
P value, diabetes by race interaction | 0.06 | ||||||
P value, prediabetes by race interaction | 0.52 | ||||||
Brachial-ankle PWV | |||||||
N | 357 | 459 | 151 | 840 | 2,030 | 753 | |
Differencea (cm/s) | 45.4 | 4.3 | 0 | 51.3 | 24.6 | 0 | |
95% CI | −13.2, 104.1 | −50.6, 59.3 | ref. | 21.3, 81.2 | 0.2, 49.1 | ref. | |
P value, diabetes by race interaction | 0.37 | ||||||
P value, prediabetes by race interaction | 0.37 | ||||||
Femoral-ankle PWV | |||||||
N | 340 | 438 | 143 | 735 | 1,868 | 694 | |
Differencea (cm/s) | −8.8 | 5.1 | 0 | −21.2 | −6.4 | 0 | |
95% CI | −45, 27.3 | −28.6, 38.9 | ref. | −40, −2.5 | −21.5, 8.8 | ref. | |
P value, diabetes by race interaction | 0.35 | ||||||
P value, prediabetes by race interaction | 0.35 |
Abbreviations: ARIC, Atherosclerosis Risk in Communities; CI, confidence interval; PWV, pulse wave velocity.
aModels adjusted for age, gender, race-center, heart rate, hypertension, smoking, and body mass index. The indicator variables for center varied by race group given the varying representation at each of the 4 centers.
bFasting glucose (FG) and glycated hemoglobin (HbA1c) criteria: (i) diabetes if FG ≥126mg/dl, or currently taking diabetes medication, or HbA1c ≥6.5%. Among those without diabetes, then (ii) prediabetes if fasting glucose 100–125mg/dl or HbA1c 5.7%–6.4%, and (iii) normal glucose if FG <100mg/dl and HbA1c <5.7%.