Fig. 3.
Sequential de novo phospholipid membrane formation and remodeling driven by nonenzymatic reactions. (A) ELSD spectra corresponding to the in situ phospholipid formation of 3. (B) ELSD spectra corresponding to the RNCL exchange reaction between in situ-formed phospholipid 3 and the N-methylated cysteine-functionalized lysolipid 4, leading to an equimolar mixture of 3 and 5. (C) ELSD spectra corresponding to the RNCL exchange reaction between in situ-formed phospholipid 3 and cysteine-functionalized lysolipid 6, leading to the selective formation of 7.