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. 2016 Jul 18;113(31):E4558–E4566. doi: 10.1073/pnas.1608319113

Table S1.

Kd values of bromodomains to BETi GS-626510

Compound name DiscoveRx gene symbol Entrez gene symbol Modifier Kd (nM)
GS-626510 ATAD2A ATAD2 > 10,000
GS-626510 ATAD2B ATAD2B > 10,000
GS-626510 BAZ2A BAZ2A > 10,000
GS-626510 BAZ2B BAZ2B > 10,000
GS-626510 BRD1 BRD1 > 10,000
GS-626510 BRD2 (1) BRD2 = 2.5
GS-626510 BRD2 (1, 2) BRD2 = 1.1
GS-626510 BRD2 (2) BRD2 = 0.59
GS-626510 BRD3 (1) BRD3 = 1.7
GS-626510 BRD3 (1, 2) BRD3 = 0.66
GS-626510 BRD3 (2) BRD3 = 0.65
GS-626510 BRD4 (1) BRD4 = 2.9
GS-626510 BRD4 (1, 2) BRD4 = 1.3
GS-626510 BRD4 (2) BRD4 = 3.2
GS-626510 BRD4 (full-length,short-iso.) BRD4 = 2.8
GS-626510 BRD7 BRD7 > 10,000
GS-626510 BRD8 (1) BRD8 = 5,900
GS-626510 BRD8 (2) BRD8 > 10,000
GS-626510 BRD9 BRD9 > 10,000
GS-626510 BRDT (1) BRDT = 19
GS-626510 BRDT (1, 2) BRDT = 4.9
GS-626510 BRDT (2) BRDT = 5
GS-626510 BRPF1 BRPF1 = 4,100
GS-626510 BRPF3 BRPF3 > 10,000
GS-626510 CECR2 CECR2 = 8,200
GS-626510 CREBBP CREBBP = 170
GS-626510 EP300 EP300 = 220
GS-626510 FALZ BPTF > 10,000
GS-626510 GCN5L2 KAT2A > 10,000
GS-626510 PBRM1 (2) PBRM1 > 10,000
GS-626510 PBRM1 (5) PBRM1 > 10,000
GS-626510 PCAF KAT2B > 10,000
GS-626510 SMARCA2 SMARCA2 > 10,000
GS-626510 SMARCA4 SMARCA4 > 10,000
GS-626510 TAF1 (2) TAF1 = 8,000
GS-626510 TAF1L (2) TAF1L > 10,000
GS-626510 TRIM24 (Bromo.) TRIM24 = 4,100
GS-626510 TRIM24 (PHD, Bromo.) TRIM24 = 6,900
GS-626510 TRIM33 (PHD, Bromo.) TRIM33 > 10,000
GS-626510 WDR9 (2) BRWD1 > 10,000