Table 5.

Relationships Between Regional Lesion Loads and % Change in BMI From Baseline to Last Visit Prior to MRI, With Covariate Adjustment for the Risk Factors in Table 1 and ICV

Region/Group by BMI % Change	Decrease > 5% (N = 376)	Change −5% and 5% (N = 745)	Increase > 5% (N = 282)	p Value
Total WM	4.7 (0.7)	4.5 (0.7)	4.8 (0.7)	.65
WM
Frontal	2.2 (0.3)	2.1 (0.3)	2.2 (0.3)	.55
Temporal	1.1 (0.2)	1.0 (0.2)	1.1 (0.2)	.63
Parietal	1.3 (0.2)	1.7 (0.2)	1.3 (0.2)	.81
Occipital	0.4 (0.1)	0.4 (0.1)	0.4 (0.1)	.59

Notes: BMI = body mass index; ICV = intracranial volume; MRI = magnetic resonance imaging; WM = white matter.