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. 2016 Aug 9;11(8):e0160502. doi: 10.1371/journal.pone.0160502

Table 2. Univariate comparison for baseline clinical and imaging data.

Poor outcome (mRS score, 3–6) Good outcome (mRS score, 0–2) p Value
(n = 56) (n = 24)
Age, y 71.5 ± 11.1 63.9 ± 10.0 0.005
Female, % 23 (41.1) 10 (41.7) 0.960
Additional ICA occlusion, % 22 (39.3) 1 (4.2) 0.001
OIT, min 176.5 (110–237) 150.5 (86.8–245) 0.605
ONT, min 203.5 (135–271) 170 (129–252) 0.755
Risk factors
Hypertension, n (%) 40 (71.4) 14 (58.3) 0.252
Diabetes, % 10 (17.9) 1 (4.2) 0.103
Atrial fibrillation, % 34 (60.7) 14 (58.3) 0.842
hyperlipidemia, % 28 (50.0) 7 (29.2) 0.085
Smoking, % 13 (23.2) 7 (29.2) 0.573
History of stroke/ TIA, % 7 (12.5) 3 (12.5) 1.000
Previous use of antiplatelet, % 5 (8.9) 4 (16.7) 0.315
baseline serum glucose, mg/mL 7.8 ± 3.6 6.8 ± 1.3 0.193
baseline SBP, mm Hg 148.3 ± 22.0 148.3 ± 21.5 0.994
baseline DBP, mm Hg 82.0 ± 12.5 85.3 ± 13.8 0.300
Baseline NIHSS 14 (12–18) 8.5 (5.25–12.0) <0.001
Baseline infarct volume, mL 73.6 (36.9–111.1) 46.9(23.0–70.0) 0.001
Baseline hypoperfusion volume, mL 153.2 (100.7–215.4) 119.4 (75.8–146.2) 0.029
Baseline mismatch ratio, % 2.89 ± 2.38 3.61 ± 3.80 0.350
rLMC-P 11 (8.25–13) 14 (12.3–15.8) <0.001
rLMC-M 14 (12–16) 17 (14–18) <0.001

ICA: internal carotid artery; OIT: onset to imaging time; ONT: onset to needle time; TIA: transient ischemic attack; SBP: systolic blood pressure; DBP: diastolic blood pressure; NIHSS: national institute of health stroke scale