Skip to main content
. 2016 Aug 9;11(8):e0160791. doi: 10.1371/journal.pone.0160791

Table 2. Number of genes subjected to GAN reconstruction and properties of resulted GANs.

method NCSRM BETR
cell line and applied radiation dose Increased sensitivity (1 Gy) normal sensitivity (1 Gy) Increased sensitivity (10 Gy) normal sensitivity (10 Gy) Increased sensitivity (1 Gy) normal sensitivity (1 Gy) Increased sensitivity (10 Gy) normal sensitivity (10 Gy)
number of genes taken for network reconstruction 2335 7 6019 3892 923 12 3889 1256
number of nodes remained in the network 1140 - 3483 2735 336 - 2299 773
number of edges in the network 12198 - 114629 84695 3268 - 126378 16862
network density 0.00939 - 0.00945 0.01133 0.02903 - 0.02392 0.02826
density of the Reactome interaction network 0.00536

Gene association network reconstructions were performed using the GeneNet method [18]. Association between two genes was considered as significant if posterior edge probability was equal or greater than 0.95. Densities of the reconstructed networks were compared with the density of the Reactome interaction network in order to assess their complexity.