Fig. 2.

In vitro studies. a Assessment of the oxidant status and cellular toxicity of MSCs after exposure to low serum or TNF alpha with or without aliskiren. Data represent mean±SEM. *p<0.05; ***p<0.001 vs. each challenge without aliskiren. b Western blot analysis of NAD(P)H oxidase p67phox and Xanthine dehydrogenase (XDH), showing that aliskiren is able to normalize the expression of proteins involved in the production of reactive oxygen species. Data represent mean±SEM. *p<0.05; **p<0.01 vs. 10 % FBS, §p<0.05 vs. 1 % FBS