Fig 1. Del1 developmental expression.

Mice at the indicated developmental stage were sacrificed and underwent LACZ staining and whole mount preparation: (A) E14.5, frontal view; (B) E14.5, side view; (C) E17.5, ribs and vertebrae; (D) E17.5, skull base, larynx and trachea, and ribs; (E) D0 transgenic newborn; (F) D0 wildtype newborn; (G) D0 transgenic paw. E17.5 embryos were sectioned, stained for LACZ as indicated by blue staining, and counterstained with hematoxylin. Images are shown of staining in the nasal cartilage (H, 25x magnification), costal cartilage (I, 100x magnification), and knee (J, 25x magnification).