Table 3. Inflammatory Markers.
| Parameter | Group | Day 1 | Day 2 | Day 3 | Day 4 |
|---|---|---|---|---|---|
| LBP [μg/l] [Median (IQR)] | Control | 23.3 * (19.3/29.5) | 36.2 (19.1/53.2) | 26.5 (19.2/40.7) | 19.2 (15.4/26.5) |
| IgM-IVIg | 41.1 * (38.4/46.3) | 36.1 (33.5/51.2) | 32.0 (24.1/33.3) | 28.0 (16.6/31.8) | |
| IL-6 [pg/μl] [Median (IQR)] | Control | 312.5 (22.2/1850.5) | 422.6 (73.9/1033.2) | 142.9 (70.1/674.7) | 75.9 (42.5/331.5) |
| IgM-IVIg | 478.6 (159.2/1025.4) | 322.4 (164.7/805.7) | 125.4 (88.9/541.3) | 99.5 (80.3/529.0) | |
| Leukocytes [/nl] [Median (IQR)] | Control | 15.1 (8.6/20.7) | 15.6 (9.8/24.0) | 15.5 (12.0/28.3) | 13.7 (10.4/19.6) |
| IgM-IVIg | 15.2 (7.1/23.2) | 15.5 (10.6/16.3) | 15.4 (9.7/20.0) | 11.7 (7.6/16.2) |
LBP, lipopolysaccharide binding protein; IL-6, interleukin-6; IQR, interquartile range; IgM-IVIg, IgM enriched intravenous immunoglobulin; Control group n = 14, IgM-IVIg group n = 12 (days 1 and 2), n = 11 (day 3) and n = 10 (day 4);
* indicating p = 0.034, as calculated using the Mann-Whitney-test