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. Author manuscript; available in PMC: 2016 Aug 9.
Published in final edited form as: Genes Immun. 2014 May 22;15(5):320–332. doi: 10.1038/gene.2014.22

FIGURE 7. Unc93b1 plays a role in mediating viral clearance and tissue inflammation but does not influence survival following influenza A/PR/8/34 (H1N1) infection.

FIGURE 7

(A) Lung viral load in Unc93b1+/+ (grey bars) and Unc93b1Letr/Letr (white bars) mice at day 3, 7, and 10 following influenza infection. (B) Survival and (C) weight loss of Unc93b1+/+ (solid line) and Unc93b1Letr/Letr (dashed line) mice over a 21-day period following influenza infection. Representative lung sections from (D, E) uninfected or (F, G) infected lungs at day 7 post-infection of (D, F) Unc93b1+/+ and (E, G) Unc93b1Letr/Letr mice. Day 7 post-infection is visualized at 4x and 10x magnification. Data is pooled from independent experiments. (A) n≥10/group, (B) n≥34/group, (C) n≥27/group. **p<0.01 determined by (A) two-tailed unpaired t-test or (B) Logrank test.