TABLE 2.
Current commercially available inhaled antibiotic formulations
| Antibiotic (trade name) | FDA indication |
|---|---|
| Aztreonam solution (Cayston) | Improvement of respiratory symptoms in patients ≥6 yr of age with CF, FEV1 of >25% and <75%, and P. aeruginosa infection |
| Colistin dry powder (Colobreathe) | Not FDA approved; approved by the EMA for management of chronic pulmonary infections due to P. aeruginosa in patients ≥6 yr of age with CF |
| Tobramycin inhalation solution (Tobi) | Management of CF patients >6 yr of age with P. aeruginosa infection with FEV1 of >25% and <75% on a 28-day alternating on/off schedule |
| Tobramycin inhalation powder (Tobi Podhaler) | Management of CF patients >6 yr of age with P. aeruginosa infection with FEV1 of >25% and <80% on a 28-day alternating on/off schedule |