Table 3.
Clinical demography of children with intracranial incidental findings on pediatric brain magnetic resonance imaging studies at pediatric specialty clinic other than neurology[16-21]
| Ref. | Study-setting | Reason for MRI | No. of subject | No. of MRI (%) |
Clinical demographics |
|
| Mean age (range) year | Girls n (%) with MRI | |||||
| Oh et al[16] | Endocrinology | Rathke’s cleft cysts | 341 | 26 (76) | NA (4-18) | 17 (65) |
| Rachmiel et al[17] | Endocrinology | Congenital hypothyroidism | 682 | 30 (100) | 12.5 (10-15) | 16 (55) |
| Whitehead et al[18] | Radiology | Pineal cyst | 100 | 100 (100) | 6.8 (1 mo-17) | 52 (52) |
| Mogensen et al[19] | Endocrinology | Early puberty | 229 | 207 (100)3 | NA (6-9) | 207 (100) |
| Perret et al[20] | Oncology | Primary brain tumor4 | 335 | 335 (100) | 7.6 (0-18) | 132 (39) |
| Jordan et al[21] | Neurology research | Sickle cell disease | 953 | 953 (100) | 9.2 (5-15) | 460 (48) |
1
76% of patient with Rathke’s cleft cysts were discovered during evaluations for endocrine disorders;
2
This includes 38 healthy boys 11.7 ± 1.7 years;
3
22 (11%) patients who had computerized tomography of the brain due to contraindication of MRI are not included in this table;
4
Central nervous system tumors were identified incidentally. MRI: Magnetic resonance imaging; NA: Not available.