Table 1.
Body weight, 1-day food intake, and blood glucose concentration
| Normal Diet Group |
High-Fat Diet Group |
||||
|---|---|---|---|---|---|
| Weeks of Treatment | Wild type | Fyn−/− | Wild type | Fyn−/− | |
| 1 | Body wt, g | 24.1 ± 0.3 | 24.0 ± 0.5 | 28.8 ± 0.6* | 28.5 ± 0.4* |
| Food intake, g | 3.1 ± 0.6 | 3.2 ± 0.5 | 4.6 ± 0.4* | 4.5 ± 0.3* | |
| Blood glucose, mmol/l | 7.4 ± 0.4 | 7.4 ± 0.3 | 7.5 ± 0.3 | 7.5 ± 0.6 | |
| 16 | Body wt, g | 36.3 ± 0.6 | 36.0 ± 0.9 | 56.1 ± 1.2* | 55.5 ± 1.8* |
| Food intake, g | 3.1 ± 0.4 | 3.3 ± 0.6 | 6.4 ± 0.4* | 6.8 ± 0.3* | |
| Blood glucose, mmol/l | 7.4 ± 0.5 | 7.6 ± 0.6 | 8.9 ± 0.5* | 8.6 ± 0.3* | |
| 24 | Body wt, g | 37.1 ± 2.1 | 37.7 ± 2.5 | 57.4 ± 2.1* | 56.7 ± 1.7* |
| Food intake, g | 3.7 ± 0.4 | 3.3 ± 0.2 | 6.9 ± 0.2* | 7.1 ± 0.2* | |
| Blood glucose, mmol/l | 7.4 ± 0.6 | 7.4 ± 0.5 | 9.0 ± 0.3* | 8.9 ± 0.6* | |
Data are expressed as means ± SE; n = 10–33 per group.
*
Significant difference relative to normal diet group (P < 0.05).