Table 2.

Parameters for the full model simulation presented in Fig. 4

Parameter	Value	Description	Reference
Input
Wext	See methods	Input current weights	N/A
σext	5 mV/R	Input current variability	N/A
MC
τMC	5 ms−1	MC membrane time constant	de Almeida et al. (2013)
τAMPA1,MC	1 ms−1	MC AMPA rise time	de Almeida et al. (2013)
τAMPA2,MC	2 ms−1	MC AMPA decay time	de Almeida et al. (2013)
EAMPA	0 mV	MC AMPA reversal potential	Brunel and Wang (2003)
τMC	0.5 ms−1	MC GABA rise time	Brunel and Wang (2003)
τMC	5 ms−1	MC GABA decay time	Brunel and Wang (2003)
EGABA	−80 mV	GABA reversal potential	Cang and Isaacson (2003)
Vrest,MC	−70 mV	MC resting potential	de Almeida et al. (2013)*
Vth,MC	−63 mV	MC firing threshold	Cang and Isaacson (2003)
Vhyper	−80 mV	MC/GCD hyperpolarization potential	de Almeida et al. (2013)*
WGABA,MC	0.0125	MC GABA inhibitory weight	N/A (varied in Figs. 6 and 8)
GCD
τGC	5 ms−1	GCD membrane time constant	de Almeida et al. (2013)
τAMPA1,GC	1 ms−1	GCD AMPA rise time	de Almeida et al. (2013)
τAMPA2,GC	2 ms−1	GCD AMPA decay time	de Almeida et al. (2013)
τNMDA1,GC	2 ms−1	GCD NMDA rise time	N/A (varied in Fig. 9)
τNMDA2,GC	75 ms−1	GCD NMDA decay time	N/A (varied in Fig. 9)
τNmax,GC	18 ms−1	GCD N-type activation time constant	Amini et al. (1999)
EAMPA	0 mV	GC AMPA reversal potential	Brunel and Wang (2003)
ENMDA	0 mV	GC NMDA reversal potential	de Almeida et al. (2013)
ECa(N)	∼ 120 mV	GC N-type reversal potential	Calculated each time step
[Ca]out	1,500 μM	External Ca2+ concentration	Zeng et al. (2009)
[Ca]th	1.5 μM	Ca2+ threshold for maximum GABA release	N/A
ρCa	100	Proportionality between ICa and [Ca2+]	N/A
Vrest,GC	Varied	GCD resting potential	N/A (varied in most figures)
WAMPA,GC	0.03	GCD AMPA excitatory weight	Cang and Isaacson (2003)
WNMDA,GC	0.04	GCD NMDA excitatory weight	N/A (varied in Fig. 8)
WN,GC	250	GCD N-type excitatory weight	N/A (varied in Fig. 8)

^*Voltages are shifted down by −70 mV from de Almeida et al. (2013) but remain the same relative distance from each other. N/A, not applicable.