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. 2016 Jul 27;2016:5378567. doi: 10.1155/2016/5378567

Figure 3.

Figure 3

Overexpression of β-catenin increased the chemoresistance of SCC-25 cells to cisplatin and promoted cell survival. (a) Overexpression of β-catenin increased the expression levels of Bcl-2, MRP-1, and MDR-1 compared to the controls. (b) Western blot analysis of the protein expression levels of Bcl-2, MRP-1, and MDR-1. (c) Expression of β-catenin was involved in the Wnt signaling pathway by regulation of GSK-3β and C-myc. (d) Western blot analysis of the protein expression levels of GSK-3β and C-myc. ∗ P < 0.05.