Figure 1.

Educated macrophages (EM) decrease LPS-induced lung inflammation. Mice were allocated and received the following treatment: control, LPS, LPS + ASCs, LPS + macrophages (M), and LPS + EM. Animals were sacrificed before and at 6, 24, and 48 h after LPS or PBS treatment. (a) Lungs were fixed in paraformaldehyde. Lung sections were stained with H&E and visualized at ×200 magnification. (b) Quantification of neutrophils per high-power field on lung sections stained with H&E. All data are expressed as mean ± SEM. ^∗ p < 0.05; ^∗∗ p < 0.01; and ^∗∗∗ p < 0.001.