Table 1. Key differences between three implementations of LDhot.
Method | Auton et al. 2012 | Auton et al. 2014 | mlehot |
---|---|---|---|
Window size | 200 kb | 100 kb | 20 kb |
P-value cutoff | 0.01 | 0.001 | 0.01 |
Max. size | 5 kb | None | None |
LDhat | Peak must be ≥5/kb | – | Intersection with 1 kb regions with ρ ≥ 5 |
Simulations | Region-specific | Region-specific | Lookup table |