Figure 3.

The relative risk of a deleterious mutation on haplotypes that carry a male-beneficial vs. a female-beneficial sexually antagonistic allele. Results show the relative enrichment of a deleterious allele on haplotypes that carry the sexually antagonistic allele A_m. The left panel shows the accumulation of a deleterious mutation with female-limited effect (t_m = 0; t_f = 0.1) under sexually symmetric mutation (u_f = u_m = 10⁻⁵). The right panel shows the accumulation of a symmetrically deleterious mutation (t_m = t_f = 0.1) under male-biased mutation (u_f = 10⁻⁵; u_m/u_f = 8). Sexually antagonistic selection is symmetric between the sexes (s_m = s_f; q_hap = q_add = q_DR = 0.5). Each curve is based on the general equation (2) (with higher terms of δ included), and the haploid or diploid model expressions in equations (4) to (6). Triangles show the results of deterministic simulations under the haploid model of inheritance; circles show simulation results under diploid inheritance, for each of the dominance scenarios considered.