Table 1. Postnatal lethality and laterality defect.

Age	P0–P1a		P10		P21
Dnaaf1m4Bei	Observedb	Expected	Observedc	Expected	Observedd	Expected
Wild-type	29	20.5	21	17.5	12	8.25
Heterozygote	39	41	43	35	21	16.5
Homozygote	14	20.5	6	17.5	0	8.25
Laterality defect	8 (57.1%)		2 (33.3%)		N/Ae
Situs inversus	3		0
Heterotaxy	5		2
Lrrc48m6Bei	Observed	Expected	Observed	Expected	Observed	Expected
Wild-type	21	18	24	19.75	22	17.75
Heterozygote	33	36	36	39.5	31	35.5
Homozygote	18	18	19	19.75	18	17.75
Laterality defect	2 (11.1%)		1 (5.3%)		N/Ae
Situs inversus	2		0
Heterotaxy	0		1

N/A, not applicable.

^aOnly one litter was P0 out of total 11 litters.

^bChi-square test, P = 0.0583 (two-tailed).

^cChi-square test, P = 0.0065 (two-tailed).

^dChi-square test, P = 0.0037 (two-tailed).

^eLaterality defect was not examined at P21.