Table 1. Functional connectivity results.
| Band/Link | FC Ratio BD group | FC Ratio CN group | Effect Size Cohen’s d | Ancova | Accuracy | Coordinates | Ttest BD | Ttest CN |
|---|---|---|---|---|---|---|---|---|
| Delta/FMC-Pc | 1.07 ± 0.07 | 0.99 ± 0.05 | Δ = 1.7 | *p < 2e-04 | 74% | FMC [−1 43 −16] Pc [9 −59 40] | *p < 1e-03 | p < 2e-01 |
| Delta/FMC-rIPL | 1.06 ± 0.08 | 0.97 ± 0.07 | Δ = 1.4 | *p < 5e-04 | 79% | FMC [−1 45 −15] rIPL [57 −57 23] | *p < 9e-03 | *p < 3e-02 |
| Theta/lIPL-FMC | 1.08 ± 0.05 | 0.98 ± 0.07 | Δ = 1.5 | *p < 6e-06 | 79% | lIPL [−56 −39 40] FMC [−1 43 −17] | *p < 5e-06 | p < 2e-01 |
| Theta/rIPL-FMC | 1.05 ± 0.06 | 0.96 ± 0.04 | Δ = 2.2 | *p < 7e-07 | 87% | rIPL [52 −46 32] FMC [−3 43 −16] | *p < 3e-03 | *p < 2e-03 |
| Theta/rIPL-Acc | 1.06 ± 0.05 | 0.97 ± 0.05 | Δ = 1.8 | *p < 3e-06 | 85% | rIPL [55 −39 34] Acc [2 19 25] | *p < 9e-04 | *p < 3e-04 |
| Theta/rIPL-Pc | 1.07 ± 0.08 | 0.96 ± 0.05 | Δ = 2.1 | *p < 3e-05 | 82% | rIPL [52 −41 38] Pc [−13 −63 20] | *p < 6e-05 | *p < 2e-02 |
| Beta/lIPL-rIPL | 1.08 ± 0.07 | 0.96 ± 0.06 | Δ = 1.8 | *p < 5e-06 | 82% | lIPL [−53 −51 30] rIPL [54 −42 35] | *p < 1e-04 | *p < 7e-04 |
| Beta/lIPL-FMC | 1.12 ± 0.14 | 0.95 ± 0.10 | Δ = 1.7 | *p < 6e-05 | 77% | lIPL [−50 −43 35] FMC [−1 43 −17] | *p < 2e-03 | *p < 3e-02 |
| Beta/rIPL-FMC | 1.11 ± 0.12 | 0.96 ± 0.09 | Δ = 1.7 | *p < 6e-05 | 77% | rIPL [56 −44 30] FMC [0 42 −18] | *p < 1e-03 | p < 6e-02 |
| Beta/rIPL-Acc | 1.09 ± 0.07 | 0.96 ± 0.04 | Δ = 3.2 | *p < 2e-08 | 87% | rIPL [54 −43 33] Acc [0 −19 25] | *p < 3e-04 | *p < 9e-03 |
| Beta/rIPL-Pc | 1.11 ± 0.09 | 0.95 ± 0.06 | Δ = 2.5 | *p < 6e-08 | 90% | rIPL [54 −40 35] Pc [1 −60 35] | *p < 5e-05 | *p < 2e-04 |
The FC ratio was calculated by means of the quotient: post FC/pre FC. ANCOVA test, with sex as covariate, was calculated between groups with the corresponding average FC ratio. The accuracy score was obtained through a logistic regression analysis with the leave-one-out cross-validation procedure. MNI coordinates of the center of each ROI were calculated in the corresponding network. One sample t-test was calculated with the ratio value of each group per each significant link. rIPL/lIPL (right/left inferior parietal lobe). Pc (precuneus). FMC (frontal middle cortex). ACC (anterior cingulate cortex).