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. 2016 Aug 10;6:30986. doi: 10.1038/srep30986

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A,B) Decrease in oxygen consumption and in carbon dioxide emission from breast cancer patients (indirect calorimetric canopy metabolism assessment) injected with amifostine vs. placebo (d = values after – values before injection). (C) Time course changes of the glucose levels in the venous blood of breast cancer patients injected with amifostine vs. placebo. (D) Time course changes of the lactate levels (final – initial value) in the venous blood of breast cancer patients injected with amifostine vs. placebo. Boxes and whiskers show min and max value, mean value and 25%/75% percentile values. One way ANOVA non parametric analysis (Kruskal-Wallis test) and the Wilcoxon matched pairs test were used to compare groups with continuous variable data.