Figure 5.
(A) Growth kinetics of NCTC liver and HepG2 hepatoma cells following irradiation with 6Gy, with and without 1 h pre-treatment with amifostine (100 μg/ml). (B) Growth kinetics of NCTC hepatocytes following silencing of the PDK1 gene, with and without 1 h pre-treatment with amifostine (100 μg/ml). (C,D) Growth kinetics of NCTC and of HepG2 hepatoma cells following silencing of the PDK1 gene, with and without 1 h pre-treatment with amifostine (100 μg/ml). (E,F) Radiation dose-response curves of NCTC and of HepG2 cells following silencing of the PDH gene.