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. 2016 Aug 10;6:30610. doi: 10.1038/srep30610

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(A,B) Enlarged mitochondria containing linearized cristae juxtaposed at nearly identical angles, and (C) linearized cristae forming various geometrical shapes, and (D) linearized IMM segments (arrows) joined by curved segments from a case of m.8344A>G (patient 4). (E) SBF-SEM image with example of linearized cristae and geometrical shapes and (F) three-dimensional reconstruction of mitochondrion in E (patient 4).