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. 2016 Aug 10;6:31267. doi: 10.1038/srep31267

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Copyright © 2016, The Author(s)

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(A) Schematic representation of the experimental design. (B) Immunohistochemistry for Ki67 and BrdU showed that rats injected with the AAV9- miR-106b~25 cluster trended toward higher hepatocyte proliferation than rats injected with the AAV9-miR-cluster control, and exhibited significantly lower hepatocyte proliferation in rats with the AAV9-miR-sponge than rats with the AAV9-miR-sponge control. Scale bar = 100 μm; original magnification 200×, Olympus. (C) Quantification of Ki67, and BrdU-positive cells at 0, 12, 36, and 96 hours after 2/3 PH. The results represent findings obtained from 5 rats. Error bars represent the SEM. *P < 0.05 and **P < 0.005.