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. 2016 Aug 10;6:31271. doi: 10.1038/srep31271

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Copyright © 2016, The Author(s)

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(A) Numerical results for the time courses of Ca²⁺ responses in the simulated control case. Stimulation occurs at 1 s. Stimulated cell (black), 4th cell (red), 8th cell (blue), 12th (green) and 16th cell (pink). [Ca²⁺]₀ is the steady state cytosolic [Ca²⁺] before stimulation. Inset presents the short time dynamics after stimulation (t₀) in lin-log scale. (B) Percentages of maximum F/F₀ (n_pSMCs = 16; n_A7r5 = 19) and [Ca²⁺]/[Ca²⁺]₀ increases, assuming 100% as the maximum level reached by the stimulated cell. Red line fits the exponential decrease with distance from the stimulated site and cell unit is estimated by taking a cell of 150 μm. (n_pSMCs = 22; n_A7r5 = 82).