Table 1. List of parameters.

Parameter	Description	Value
F	Maximal rate of activation-dependent Ca2+ influx11	3,45 μM.s−1
Kr	Half-saturation constant for agonist-dependent Ca2+ entry11	1,0 μM
GCa	Whole-cell conductance for VOCCs11	0,036195 μM.mV−1.s−1
	Reversal potential for VOCCs	100,0 mV
	Half-point of the VOCC activation sigmoidal11	−24,0 mV
RCa	Maximum slope of the VOCC activation sigmoidal11	8,5 mV
GNa/Ca	Whole-cell conductance for the Na+/Ca2+ exchanger11	0,006 μM.mV−1.s−1
cNa/Ca	Half-point for activation of Na+/Ca2+ exchanger by Ca2+ 11	0,5 μM
vNa/Ca	Reversal potential for the Na+/Ca2+ exchanger11	−30,0 mV
B	SR uptake rate constant	2,025 μM.s−1
cb	Half-point of the SR ATPase activation sigmoidal11	1,0 μM
C	CICR rate constant11	1545,0 μM.s−1
sc	Half-point of the CICR Ca2+ efflux sigmoidal11	2,0 μM
cc	Half-point of the CICR activation sigmoidal11	0,9 μM
D	Rate constant for Ca2+ extrusion by the ATPase pump11	3,6 s−1
vd	Intercept of voltage dependence of extrusion ATPase	−100,0 mV
Rd	Slope of voltage dependence of extrusion ATPase11	250,0 mV
L	Leak from SR rate constant11	0,375 s−1
γ	Scaling factor relating net movement of ion fluxes11	492,5 mV.μM−1
	membrane potential (inversely related to cell capacitance)
FNa/K	Net whole-cell flux via the Na+-K+-ATPase11	0,03 μM.s−1
GCl	Whole-cell conductance for Cl− current11	0,6 μM.mV−1.s−1
cCl	Ca2+ sensitivity for Cl− channels11	0,7 μM
vCl	Reversal potential for Cl− channels11	−25,0 mV
GK	Whole-cell conductance for K+ efflux11	0,045 μM.mV−1.s−1
vK	Reversal potential for K+ 11	−94 mV
λ	Rate constant for net KCa channel opening11	675
cw	Translation factor for Ca2+ dependence of KCa11	0,0 μM
	channel activation sigmoidal11
β	Translation factor for the membrane potential dependence11	0,001 μM2
	of KCa channel activation sigmoidal11
	Half-point for the KCa channel activation sigmoidal11	−27,0 mV
RK	Maximum slope of the KCa activation sigmoidal11	12,0 mV
Gback	Whole-cell conductance for background currents40,41	0,0045 μM.mV−1.s−1
vrest	Equilibrium potential11	−55,0 mV
k	Rate constant of IP3 degradation11	0,1 s−1
g	Electrical coupling coefficient11	1000 s−1