Table 3.

Genome-Wide Significant Single Nucleotide Polymorphisms and Association with CYP2A6 Expression^a

SNP	rs12459249	rs56113850	rs4001921b
GWS locus	proximal	intronic	Intergenic
Lung effect	−0.15	−0.28	−0.24
Lung P	0.037	0.00048	0.0019
Liver effect	−0.14	−0.23	−0.22
Liver P	0.091	0.00038	0.016

^aFrom GTEx.

^b r ² = 0.92, 0.98, and 0.91 with rs7247098 in AFR, EAS, and EUR 1000 Genome Project populations.