Table 3. The distribution of positive cases (i.e. either in accordance or not with the hypotheses tested) for the clade statistics reported in Table 2.

	p.dist	area.test	net.t	slope.test
% significant shifts	66.67	93.33	93.33	80
p.value (binomial test)	0.0280	≪0.0001	≪0.0001	0.0351
% significant clades	76.19	95.24	1	66.67
p.value (binomial test)	0.0279	≪0.0001	≪0.0001	0.1890

The statistical comparison is made according to the binomial distribution, given a priori success ratio of 0.5. Binomial tests are computed for both individual shiftpoints, and for clades. For the latter each hypothesis is assumed to be verified if at least one shiftpoint complies with the predictions. Values in bold indicate compliance to weak directionality theory.