Table 2. Univariate and multivariate analyses of prognostic parameters for survival in patients with gastrointestinal stromal tumor (GIST).
Prognostic parameter | Univariate analysis |
Multivariate analysis |
||||
---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Expression of CCBE1 | 4.196 | 1.574–11.185 | 0.004 | 1.816 | 0.642–5.132 | 0.260 |
Age | 1.691 | 0.759–3.766 | 0.199 | |||
Gender | 0.424 | 0.177–1.016 | 0.054 | |||
Modified NIH criteria | 7.930 | 2.394–26.268 | 0.001 | 0.398 | 0.064–2.475 | 0.323 |
Tumor Size | 6.902 | 3.382–14.083 | <0.001 | 2.689 | 1.014–7.129 | 0.047 |
Tumor location | 1.235 | 0.833–1.829 | 0.293 | |||
Mitoses per 50 HPFs | 5.284 | 3.195–8.738 | <0.001 | 3.060 | 1.454–6.437 | 0.003 |
Tumor bleeding | 0.399 | 0.094–1.696 | 0.213 | |||
NIH invasion | 3.701 | 2.198–6.231 | <0.001 | 0.924 | 0.345–2.479 | 0.875 |
Recurrence | 238.780 | 30.701–1857.105 | <0.001 | 164.389 | 13.218–2044.392 | <0.001 |
Ki67 classification | 3.157 | 2.033–4.902 | <0.001 | 0.915 | 0.571–1.467 | 0.712 |
HR: Hazard ratio; CI: Confidence interval. The bold number represents the P-values with significant differences.